{"id":84766,"date":"2024-10-18T10:02:27","date_gmt":"2024-10-18T01:02:27","guid":{"rendered":"https:\/\/japan-indepth.jp\/?p=84766"},"modified":"2024-10-18T10:04:57","modified_gmt":"2024-10-18T01:04:57","slug":"%e3%83%9c%e3%82%b9%e3%83%88%e3%83%b3%e3%83%bb%e3%82%a6%e3%82%a7%e3%83%ab%e3%83%8d%e3%82%b9%e9%80%9a%e4%bf%a1%e3%81%9d%e3%81%ae13-%e4%ba%ba%e6%b0%97%e3%81%ae%e7%97%a9%e3%81%9b%e8%96%ac%e3%80%81","status":"publish","type":"post","link":"https:\/\/japan-indepth.jp\/?p=84766","title":{"rendered":"\u30dc\u30b9\u30c8\u30f3\u30fb\u30a6\u30a7\u30eb\u30cd\u30b9\u901a\u4fe1\u305d\u306e13  \u4eba\u6c17\u306e\u75e9\u305b\u85ac\u3001\u3068\u540c\u3058\u52b9\u679c\u304c\u3042\u308b\u98df\u3079\u7269"},"content":{"rendered":"<div class=\"e6f52dc566d20a520ffae7bd1dec9ffb\" data-index=\"3\" style=\"float: none; margin:5px 0 5px 0; text-align:center;\">\n<!-- A_728*90 -->\r\n<div class=\"ad-set\">\r\n<style type=\"text\/css\">\r\n.adslot_2 { width: 100%; height: 94px; text-align:center !important;}\r\n@media (min-width:500px) { .adslot_2 { width: 468px; height: 60px; } }\r\n@media (min-width:800px) { .adslot_2 { width: 728px; height: 90px; } }\r\n<\/style>\r\n\r\n<script async src=\"\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\r\n<!-- \u8a18\u4e8b\u672c\u6587_\u4e0b\u90e8728*90 -->\r\n<ins class=\"adsbygoogle adslot_2\"\r\n     style=\"display:inline-block\"\r\n     data-ad-client=\"ca-pub-9758356432339035\"\r\n     data-ad-slot=\"4435139705\"><\/ins>\r\n<script>\r\n(adsbygoogle = window.adsbygoogle || []).push({});\r\n<\/script>\r\n\r\n<!--\r\n<ins class=\"adsbygoogle adslot_2\" style=\"display:inline-block\"; data-ad-client=\"ca-pub-9758356432339035\" data-ad-slot=\"4435139705\"><\/ins>\r\n<script async src=\"\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js\"><\/script>\r\n<script>(adsbygoogle = window.adsbygoogle || []).push({});<\/script>\r\n-->\r\n<\/div>\n<\/div>\n\n<p><b><\/b><\/p>\n<p style=\"text-align: right;\"><a href=\"https:\/\/japan-indepth.jp\/?tag=%E5%A4%A7%E8%A5%BF%E7%9D%A6%E5%AD%90\" data-rich-text-format-boundary=\"true\">\u5927\u897f\u7766\u5b50<\/a>\uff08\u7c73\u56fd\u30dc\u30b9\u30c8\u30f3\u5728\u4f4f\u5185\u79d1\u533b\u5e2b\uff09<\/p>\n<p><strong>\u3010\u307e\u3068\u3081\u3011<\/strong><\/p>\n<p>\u30fb<strong>\u30b0\u30eb\u30ab\u30b4\u30f3\u69d8\u30da\u30d7\u30c1\u30c91\uff08GLP-1\uff09\u95a2\u9023\u306e\u30c0\u30a4\u30a8\u30c3\u30c8\u60c5\u5831\u3092\u3054\u7d39\u4ecb\u3059\u308b\u3002<\/strong><\/p>\n<p><strong>\u30fbGLP-1\u30db\u30eb\u30e2\u30f3\u306e\u5206\u6ccc\u3092\u5897\u3084\u3059\u305f\u3081\u306b\u306f\u3001\u98df\u7269\u7e4a\u7dad\u3084\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u542b\u3080\u98df\u54c1\u304c\u52b9\u679c\u7684\u3067\u3042\u308b\u3002<\/strong><\/p>\n<p><strong>\u30fb\u7279\u306b\u3001\u767a\u9175\u6027\u98df\u7269\u7e4a\u7dad\u3084\u826f\u8cea\u306a\u8102\u8cea\u3092\u6442\u53d6\u3057\u3001\u70ad\u6c34\u5316\u7269\u524d\u306b\u91ce\u83dc\u3092\u98df\u3079\u308b\u3053\u3068\u304c\u63a8\u5968\u3055\u308c\u308b\u3002<\/strong><\/p>\n<p><strong>\u00a0<\/strong><\/p>\n<p>\u3000\u5148\u65e5\u5916\u6765\u3067\u300140\u4ee3\u5f8c\u534a\u306e\u5973\u6027A\u3055\u3093\u306b\u300c\u66f4\u5e74\u671f\u306b\u306a\u3063\u3066\u4f53\u91cd\u304c\u5897\u3048\u307e\u3057\u305f\u3002\u306a\u308b\u3079\u304f\u85ac\u3092\u4f7f\u308f\u305a\u306b\u3001\u98df\u4e8b\u3092\u5909\u3048\u3066\u81ea\u7136\u306b\u4f53\u91cd\u3092\u6e1b\u3089\u3057\u305f\u3044\u3067\u3059\u3002\u3069\u3093\u306a\u98df\u4e8b\u304c\u304a\u52e7\u3081\u3067\u3059\u304b\uff1f\u300d\u3068\u3044\u3046\u8cea\u554f\u3092\u53d7\u3051\u307e\u3057\u305f\u3002<\/p>\n<p>\u305d\u3053\u3067\u4eca\u56de\u306f\u3001A\u3055\u3093\u306e\u3088\u3046\u306a\u60a9\u307f\u3092\u62b1\u3048\u3066\u3044\u308b\u4eba\u306b\u3001\u6700\u8fd1\u7c73\u56fd\u3067\u30db\u30c3\u30c8\u306a<strong>\u30b0\u30eb\u30ab\u30b4\u30f3\u69d8\u30da\u30d7\u30c1\u30c91\uff08GLP-1\uff09\u95a2\u9023\u306e\u30c0\u30a4\u30a8\u30c3\u30c8\u60c5\u5831<\/strong>\u3092\u3054\u7d39\u4ecb\u3057\u307e\u3059\u3002<\/p>\n<p>\u00a0<\/p>\n<ul>\n<li>\u4f53\u5185\u306eGLP-1\u306f\u98df\u4e8b\u3067\u5897\u3084\u305b\u308b\uff1f<\/li>\n<\/ul>\n<p>\u3000\u4e16\u754c\u4e2d\u306b\u5927\u65cb\u98a8\u3092\u5dfb\u304d\u8d77\u3053\u3057\u3066\u3044\u308b\u300cGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u300d\u3002\uff12\u578b\u7cd6\u5c3f\u75c5\u3092\u60a3\u3046\u4eba\u306e\u8840\u7cd6\u5024\u3068\u4f53\u91cd\u306e\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3001\u80a5\u6e80\u306e\u4eba\u306e\u6e1b\u91cf\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002<\/p>\n<p>\u3000\u3068\u3053\u308d\u3067\u3001\u305d\u3082\u305d\u3082GLP-1\u306f\u3001\u79c1\u305f\u3061\u304c\u98df\u3079\u7269\u3092\u6442\u53d6\u3059\u308b\u3068\u3001\u8133\u3084\u6d88\u5316\u7ba1\u3067\u4f5c\u3089\u308c\u308b\u30db\u30eb\u30e2\u30f3\u3067\u3059\u3002\u305d\u306e\u4fe1\u53f7\u306f\u3001\u81b5\u81d3\u304b\u3089\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u653e\u51fa\u3092\u523a\u6fc0\u3057\u3001\u8840\u7cd6\u5024\u3092\u4e0a\u3052\u308b\u30db\u30eb\u30e2\u30f3\u306e\u30b0\u30eb\u30ab\u30b4\u30f3\u306e\u653e\u51fa\u3092\u6e1b\u3089\u3059\u3053\u3068\u3092\u6307\u793a\u3057\u307e\u3059\u3002\u307e\u305f\u3001\u80c3\u304b\u3089\u8178\u3078\u306e\u98df\u7269\u306e\u6d88\u5316\u3092\u9045\u3089\u305b\u308b\u305f\u3081\u3001\u6e80\u8179\u611f\u304c\u65e9\u304f\u611f\u3058\u3089\u308c\u3001\u3057\u304b\u3082\u9577\u304f\u7d9a\u304d\u307e\u3059\u3002\u3053\u3046\u3057\u3066GLP-1 \u304c\u5897\u3048\u308b\u3068\u7a7a\u8179\u611f\u304c\u6e1b\u308a\u3001\u8840\u7cd6\u5024\u304c\u5b89\u5b9a\u3057\u3001\u4f53\u91cd\u3092\u3088\u308a\u9069\u5207\u306b\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n<p>\u3000GLP-1 \u306e\u8840\u4e2d\u6fc3\u5ea6\u306f\u3001\u7a7a\u8179\u6642\u306f\u4e00\u822c\u306b 5 pmol\/L \u304b\u3089 15 pmol\/L \u306e\u7bc4\u56f2\u306b\u3042\u308a\u3001\u98df\u5f8c\u306f 2 \u500d\u304b\u3089 4 \u500d\u306b\u5897\u3048\u307e\u3059\uff08\uff11\uff09\u3002\u3088\u308a\u5177\u4f53\u7684\u306b\u306f\u3001GLP-1 \u306e\u8840\u4e2d\u6fc3\u5ea6\u306f\u98df\u5f8c 15 \u5206\u4ee5\u5185\u306b\u4e0a\u6607\u3057\u3001\u7d04 60 \u5206\u5f8c\u306b\u30d4\u30fc\u30af\u306b\u9054\u3057\u307e\u3059\u30022 \u6642\u9593\u5f8c\u306b\u306f\u3001GLP-1 \u6fc3\u5ea6\u306f\u6b21\u306e\u98df\u4e8b\u307e\u3067\u5f90\u3005\u306b\u4f4e\u4e0b\u3057\u59cb\u3081\u307e\u3059\uff08\uff11\uff09\u3002\u305f\u3060\u3057\u4f53\u304c\u5341\u5206\u306a GLP-1 \u3092\u751f\u6210\u3057\u306a\u3044\u3068\u3001\u6e80\u8179\u306e\u5408\u56f3\u304c\u4f53\u306b\u4f1d\u308f\u3089\u305a\u3001\u98df\u3079\u7d9a\u3051\u3066\u3057\u307e\u3046\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>\u3000\u4e00\u65b9\u3001GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u306e\u534a\u6e1b\u671f\u306f\u306f\u308b\u304b\u306b\u9577\u304f\u3001\u85ac\u5264\u306e\u7a2e\u985e\u306b\u3088\u3063\u3066 \u9055\u3044\u307e\u3059\u304c\u30011.5 \u6642\u9593\u304b\u3089 5 \u65e5\u9593\u6301\u7d9a\u3057\u307e\u3059\u3002\u3053\u306e\u5b89\u5b9a\u6027\u3067\u3001\u85ac\u306f\u98df\u6b32\u3068\u6e07\u671b\u3092\u6291\u3048\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\uff08\uff12\uff09\u3002<\/p>\n<p>\u3000\u3068\u306f\u3044\u3048\u5b09\u3057\u3044\u30cb\u30e5\u30fc\u30b9\u304c\u3042\u308a\u307e\u3059\u3002<strong>\u98df\u4e8b\u3067\u4f53\u5185\u306e GLP-1 \u751f\u6210\u3092\u5897\u3084\u3059\u3053\u3068\u304c\u3067\u304d\u308b\u306e\u3067\u3059\u3002<\/strong><\/p>\n<p>\u00a0<\/p>\n<ul>\n<li>\u767d\u30d1\u30f3 VS\u30e9\u30a4\u9ea6\u30d1\u30f3<\/li>\n<\/ul>\n<p>\u3000\u4ee5\u4e0b\u3001NPR\u30cb\u30e5\u30fc\u30b9\u306b\u5c02\u9580\u5bb6\u3089\u304c\u98df\u5f8c\u306eGLP-1\u306e\u53cd\u5fdc\u3092\u8aac\u660e\u3057\u3066\u3044\u307e\u3059\uff08\uff13\uff09\u3002<\/p>\n<p>\u3000\u671d\u8d77\u304d\u3066\u7a7a\u8179\u3092\u611f\u3058\u3001\u767d\u30d1\u30f3 2 \u679a\u3068\u76ee\u7389\u713c\u304d\u3092\u98df\u3079\u305f\u3068\u3057\u307e\u3059\u3002\u6d88\u5316\u3055\u308c\u305f\u98df\u7269\u304c\u5c0f\u8178\u306b\u5165\u308a\u3001\u70ad\u6c34\u5316\u7269\u3001\u8102\u80aa\u3001\u30a2\u30df\u30ce\u9178\u306a\u3069\u306e\u6804\u990a\u7d20\u306e\u591a\u304f\u304c\u8840\u6db2\u3068\u8133\u3067\u96ea\u5d29\u306e\u3088\u3046\u306a\u6d3b\u52d5\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059\u3002\u305d\u3057\u3066\u3001GLP-1\u306a\u3069\u306e\u30db\u30eb\u30e2\u30f3\u304c\u653e\u51fa\u3055\u308c\u307e\u3059\u3002<\/p>\n<p>\u3000\u30df\u30c3\u30c9\u30a6\u30a7\u30b9\u30bf\u30f3\u5927\u5b66\u306e\u8178\u751f\u7406\u5b66\u8005\u30b7\u30f3\u30b8\u30e5\u30fb\u30b9\u30f3\u30c0\u30ec\u30b5\u30f3\u535a\u58eb\u306f\u3001\u300c\u98df\u3079\u7269\u306f\u8178\u306e\u7d30\u80de\u3092\u6d3b\u6027\u5316\u3057\u3001\u305d\u3053\u304b\u3089\u5927\u91cf\u306e\u30db\u30eb\u30e2\u30f3\u3092\u5206\u6ccc\u3057\u307e\u3059\u300d\u300cGLP-1\u306a\u3069\u7d0420\u7a2e\u985e\u306e\u30db\u30eb\u30e2\u30f3\u306f\u3001\u6e80\u8179\u30db\u30eb\u30e2\u30f3\u3068\u3057\u3066\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u98df\u3079\u308b\u30b9\u30d4\u30fc\u30c9\u304c\u9045\u304f\u306a\u308a\u3001\u3084\u304c\u3066\u6e80\u8db3\u611f\u3092\u611f\u3058\u3066\u98df\u3079\u308b\u306e\u3092\u3084\u3081\u308b\u306e\u3067\u3059\u300d\u3068\u8a9e\u308a\u307e\u3059\uff08\uff13\uff09\u3002<\/p>\n<p>\u3000\u305f\u3060\u3057\u3001GLP-1 \u306e\u4f5c\u7528\u306f\u975e\u5e38\u306b\u901f\u3044\u3002\u30b3\u30ed\u30e9\u30c9\u5927\u5b66\u30c0\u30fc\u30ea\u30fc\u30f3 \u30b5\u30f3\u30c9\u30d0\u30eb\u535a\u58eb\u306f\u300c\u30db\u30eb\u30e2\u30f3\u304c\u8840\u6db2\u306b\u5165\u308b\u3068\u3001\u5206\u89e3\u304c\u59cb\u307e\u308a\u307e\u3059\u300d\u300cGLP-1 \u304c\u5fc3\u81d3\u3084\u8840\u6db2\u5faa\u74b0\u306e\u6b8b\u308a\u306e\u90e8\u5206\u306b\u5230\u9054\u3059\u308b\u9803\u306b\u306f\u3001\u307b\u3068\u3093\u3069\u6b8b\u3063\u3066\u3044\u307e\u305b\u3093\u300d\u3068\u8a00\u3044\u307e\u3059\uff08\uff13\uff09\u3002\u305d\u306e\u305f\u3081\u3001\u3053\u306e\u7e4a\u7dad\u8cea\u306e\u306a\u3044\u671d\u98df\u3092\u98df\u3079\u3066\u304b\u3089 1 \uff5e 2 \u6642\u9593\u5f8c\u306b\u306f\u3001\u8840\u4e2d\u306e GLP-1 \u30ec\u30d9\u30eb\u304c\u6025\u6fc0\u306b\u4f4e\u4e0b\u3057\u307e\u3059\u3002\u305d\u3057\u3066\u663c\u98df\u306e\u6642\u9593\u306b\u306a\u308b\u3068\u3001\u307e\u305f\u7a7a\u8179\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n<p>\u3000\u3068\u3053\u308d\u304c\u767d\u30d1\u30f3\u306e\u4ee3\u308f\u308a\u306b\u3001\u98df\u7269\u7e4a\u7dad\u304c8\uff5e10\u30b0\u30e9\u30e0\u5165\u3063\u305f\u30e9\u30a4\u9ea6\u30d1\u30f3\u30922\u5207\u308c\u98df\u3079\u305f\u3089\u3069\u3046\u306a\u308b\u3067\u3057\u3087\u3046\uff1f\u5927\u91cf\u306e\u7e4a\u7dad\u3092\u8ffd\u52a0\u3059\u308b\u3068\u3001\u98df\u4e8b\u304b\u3089\u4f55\u6642\u9593\u3082\u7d4c\u3063\u3066\u304b\u3089\u8178\u304c GLP-1 \u3092\u653e\u51fa\u3057\u307e\u3059\u3002\u79c1\u305f\u3061\u306e\u4f53\u306f\u98df\u7269\u7e4a\u7dad\u3092\u5206\u89e3\u3059\u308b\u80fd\u529b\u304c\u3042\u308a\u307e\u305b\u3093\u3002\u305d\u306e\u305f\u3081\u98df\u7269\u7e4a\u7dad\u306f\u5c0f\u8178\u3092\u307b\u3068\u3093\u3069\u5909\u5316\u305b\u305a\u306b\u901a\u904e\u3057\u3001\u6700\u7d42\u7684\u306b\u306f\u98df\u5f8c\u7d04 4 \uff5e 10 \u6642\u9593\u3067\u5927\u8178\u306b\u5230\u9054\u3057\u307e\u3059\u3002<\/p>\n<p>\u3000\u98df\u7269\u7e4a\u7dad\u306f\u5927\u8178\u3067\u3001\u98df\u7269\u7e4a\u7dad\u3092\u6d88\u5316\u3059\u308b\u7d30\u83cc\u305f\u3061\u3068\u51fa\u4f1a\u3044\u307e\u3059\u3002\u7d30\u83cc\u305f\u3061\u306f\u3001\u7279\u5b9a\u306e\u98df\u7269\u7e4a\u7dad\u3092\u3088\u308a\u5c0f\u3055\u306a\u5206\u5b50\u306b\u5206\u89e3\u3057\u3001GLP-1\u3060\u3051\u3067\u306a\u304f\u3001PYY\uff08\u30da\u30d7\u30c1\u30c9YY\uff09\u3068\u547c\u3070\u308c\u308b\u98df\u6b32\u3092\u6e1b\u3089\u3059\u3082\u3046\u4e00\u3064\u306e\u91cd\u8981\u306a\u30db\u30eb\u30e2\u30f3\u306e\u653e\u51fa\u3092\u8a98\u767a\u3057\u307e\u3059\u3002<\/p>\n<p>\u3000GLP-1 \u3068 PYY \u306f\u98df\u5f8c\u6570\u6642\u9593\u5f8c\u306b\u8d77\u3053\u308b\u305f\u3081\u3001\u98df\u9593\u306e\u7a7a\u8179\u611f\u3001\u3055\u3089\u306b\u306f\u6b21\u306e\u98df\u4e8b\u306e\u98df\u6b32\u3055\u3048\u3082\u6291\u3048\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>\n<p>\u3000<strong>\u3064\u307e\u308a\u3001\u98df\u4e8b\u3067\u4f53\u5185\u306e GLP-1 \u751f\u6210\u3092\u5897\u3084\u3059\u9375\u306e\u4e00\u3064\u306f\u300c\u98df\u7269\u7e4a\u7dad\u300d\u3068\u306a\u308a\u307e\u3059\u3002<\/strong><\/p>\n<p>\u00a0<\/p>\n<ul>\n<li>GLP-1\u3092\u5897\u3084\u3059\u98df\u54c1\uff11\uff1a\u767a\u9175\u6027\u98df\u7269\u7e4a\u7dad<\/li>\n<\/ul>\n<p>\u3000\u305f\u3060\u3057\u3001\u3059\u3079\u3066\u306e\u98df\u7269\u7e4a\u7dad\u304c\u540c\u3058\u3068\u3044\u3046\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<strong>\u6e80\u8179\u30db\u30eb\u30e2\u30f3\u3092\u9ad8\u3081\u308b\u306b\u306f\u3001\u8178\u5185\u7d30\u83cc\u304c\u6d88\u5316\u3067\u304d\u308b\u300c\u767a\u9175\u6027\u98df\u7269\u7e4a\u7dad\u300d\u3092\u6442\u53d6\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/strong>\u767a\u9175\u6027\u98df\u7269\u7e4a\u7dad\u306f\u3001\u8178\u5185\u306e\u5584\u7389\u83cc\u306e\u30a8\u30b5\u3068\u306a\u308b\u98df\u7269\u7e4a\u7dad\u3067\u3059\u3002<\/p>\n<p>\u3000\u4f8b\u3048\u3070\u3001\u30aa\u30fc\u30c8\u30df\u30fc\u30eb\u306f\u30aa\u30fc\u30c4\u9ea6\u3092\u98df\u3079\u3084\u3059\u304f\u52a0\u5de5\u3057\u305f\u98df\u54c1\u3067\u3059\u304c\u3001\u767a\u9175\u6027\u98df\u7269\u7e4a\u7dad\u3092\u591a\u304f\u542b\u307f\u307e\u3059\u3002\u30eb\u30a4\u30b8\u30a2\u30ca\u5dde\u7acb\u5927\u5b66\u306e\u7814\u7a76\u8005\u306f\u3001\u5065\u5eb7\u306a\u82e5\u5e74\u6210\u4eba\u3092\u5bfe\u8c61\u306b\u3001\u30aa\u30fc\u30c8\u30df\u30fc\u30eb\u3068\u3001\u540c\u30ab\u30ed\u30ea\u30fc\u306e\u5373\u5e2d\u671d\u98df\u30b7\u30ea\u30a2\u30eb\uff08\u4f4e\u7e4a\u7dad\uff09\u306e\u98df\u6b32\u53cd\u5fdc\u3092\u6bd4\u8f03\u3057\u307e\u3057\u305f\u3002\u7d50\u679c\u3001\u5373\u5e2d\u671d\u98df\u30b7\u30ea\u30a2\u30eb\u3068\u6bd4\u8f03\u3057\u3066\u3001\u30aa\u30fc\u30c8\u30df\u30fc\u30eb\u306f\u98df\u6b32\u3092\u6291\u5236\u3057\u3001\u6e80\u8179\u611f\u3092\u9ad8\u3081\u3001\u30a8\u30cd\u30eb\u30ae\u30fc\u6442\u53d6\u91cf\u3092\u6e1b\u3089\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>\u3000\u767a\u9175\u6027\u98df\u7269\u7e4a\u7dad\u3092\u591a\u304f\u542b\u3080\u98df\u54c1\u306e\u30ea\u30b9\u30c8\uff08\uff16\uff09\u306f\u6b21\u306e\u3068\u304a\u308a\u3067\u3059\u3002<\/p>\n<p>\u30ea\u30f3\u30b4<\/p>\n<p>\u30a2\u30fc\u30c6\u30a3\u30c1\u30e7\u30fc\u30af<\/p>\n<p>\u30a2\u30b9\u30d1\u30e9\u30ac\u30b9<\/p>\n<p>\u5927\u9ea6<\/p>\n<p>\u8c46<\/p>\n<p>\u30d9\u30ea\u30fc\u985e<\/p>\n<p>\u30ad\u30e3\u30d9\u30c4<\/p>\n<p>\u30cb\u30f3\u30b8\u30f3<\/p>\n<p>\u67d1\u6a58\u985e<\/p>\n<p>\u4e9c\u9ebb\u4ec1<\/p>\n<p>\u30cb\u30f3\u30cb\u30af<\/p>\n<p>\u30ec\u30f3\u30ba\u8c46<\/p>\n<p>\u30aa\u30fc\u30c8\u9ea6<\/p>\n<p>\u30bf\u30de\u30cd\u30ae<\/p>\n<p>\u6839\u83dc\u985e<\/p>\n<p>\u3000\u3053\u308c\u3089\u306f\u307b\u3093\u306e\u4e00\u90e8\u306e\u4f8b\u3067\u3059\u3002\u591a\u304f\u306e\u679c\u7269\u3084\u91ce\u83dc\u306b\u306f\u767a\u9175\u6027\u98df\u7269\u7e4a\u7dad\u304c\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u00a0<\/p>\n<ul>\n<li>GLP-1\u3092\u5897\u3084\u3059\u98df\u54c1\uff12\uff1a\u30bf\u30f3\u30d1\u30af\u8cea<\/li>\n<\/ul>\n<p>\u3000<strong>\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u591a\u304f\u542b\u3080\u98df\u4e8b\u306f GLP-1 \u306e\u5206\u6ccc\u3092\u5927\u5e45\u306b\u523a\u6fc0\u3057\uff08\uff17\uff09\u3001\u8840\u7cd6\u5024\u306e\u4f4e\u4e0b\u3084\u6e80\u8179\u611f\u3092\u9ad8\u3081\u307e\u3059\u3002<\/strong><\/p>\n<p>\u3000\u4f8b\u3048\u3070\u3001\u5375\u3002\u30bb\u30f3\u30c8\u30eb\u30a4\u30b9\u5927\u5b66\u306e\u7814\u7a76\u8005\u3089\u306e\u3001\u592a\u308a\u3059\u304e\u3084\u80a5\u6e80\u306e\u53c2\u52a0\u8005\uff0825\uff5e60\u6b73\u306eBMI\u304c25 kg\/m2\u4ee5\u4e0a\u306e\u5973\u602730\u540d\uff09\u3092\u5bfe\u8c61\u306b\u3057\u305f\u8abf\u67fb\u3067\u306f\u3001\u5375\u306e\u671d\u98df\u306f\u3001\u540c\u30ab\u30ed\u30ea\u30fc\u306e\u30d9\u30fc\u30b0\u30eb\u30d9\u30fc\u30b9\u306e\u671d\u98df\u3068\u6bd4\u8f03\u3057\u3066\u3001\u6e80\u8179\u611f\u3092\u9ad8\u3081\u3001\u98df\u6b32\u3092\u6e1b\u3089\u3057\u3001\u305d\u306e\u5f8c\u306e\u77ed\u671f\u7684\u306a\u30a8\u30cd\u30eb\u30ae\u30fc\u6442\u53d6\u3092\u5927\u5e45\u306b\u6e1b\u3089\u3057\u307e\u3057\u305f\uff08\uff18\uff09\u3002<\/p>\n<p>\u3000\u9ad8\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u98df\u54c1\u306b\u306f\u3001\u8c46\u985e\u3001\u30ca\u30c3\u30c4\u30fb\u7a2e\u5b50\u985e\u3001\u9d8f\u8089\u3001\u9b5a\u3001\u4e73\u88fd\u54c1\u3001\u5927\u8c46\u88fd\u54c1\u304c\u3042\u308a\u307e\u3059\uff08\uff19\uff09\u3002<\/p>\n<p>\u00a0<\/p>\n<ul>\n<li>GLP-1\u3092\u5897\u3084\u3059\u98df\u54c13\uff1a\u8102\u8cea<\/li>\n<\/ul>\n<p>\u3000\u98df\u54c1\u306e\u7a2e\u985e\u306b\u3088\u3063\u3066\u306f\u3001\u3088\u308a\u591a\u304f\u306eGLP-1 \u3092\u81ea\u7136\u306b\u5897\u3084\u3057\u307e\u3059\u3002\u30c7\u30f3\u30de\u30fc\u30af\u306e\u7814\u7a76\u8005\u3089\u306b\u3088\u308b\u5831\u544a\u306b\u3088\u308b\u3068\u3001\u30aa\u30ea\u30fc\u30d6\u30aa\u30a4\u30eb\u306b\u542b\u307e\u308c\u308b\u3088\u3046\u306a\u4e0d\u98fd\u548c\u8102\u80aa\u9178\u306f\u3001\u30d0\u30bf\u30fc\u306e\u3088\u3046\u306a\u98fd\u548c\u8102\u80aa\u9178\u3088\u308a\u3082GLP-1\u306e\u653e\u51fa\u3092\u523a\u6fc0\u3059\u308b\u52b9\u679c\u304c\u9ad8\u3044\u3053\u3068\u3092\u793a\u5506\u3057\u3066\u3044\u307e\u3059\uff08\uff11\uff10\uff09\u3002<\/p>\n<p>\u30002016 \u5e74\u306e\u5831\u544a\u306b\u3088\u308b\u3068\u3001\u4f8b\u3048\u3070\u30a2\u30fc\u30e2\u30f3\u30c9\uff0830.0\uff5e90.0 g\uff09\u3084\u30d4\u30b9\u30bf\u30c1\u30aa\uff0828.0\uff5e85.0 g\uff09\u306e\u3088\u3046\u306b\u30bf\u30f3\u30d1\u30af\u8cea\u3001\u591a\u4fa1\u4e0d\u98fd\u548c\u8102\u80aa\u9178\u3001\u7e4a\u7dad\u542b\u6709\u91cf\u306e\u9ad8\u3044\u98df\u54c1\u3092\u9ad8\u70ad\u6c34\u5316\u7269\u306e\u98df\u4e8b\u306b\u52a0\u3048\u308b\u3068\u3001\u7528\u91cf\u4f9d\u5b58\u7684\u306b\u98df\u5f8c\u8840\u7cd6\u53cd\u5fdc\u304c\u6539\u5584\u3055\u308c\u308b\u3053\u3068\u3082\u793a\u3055\u308c\u3066\u3044\u307e\u3059\uff08\uff11\uff11\uff09\u3002<\/p>\n<p>\u3000\u307e\u305f\u80a5\u6e80\u306e\u5973\u6027\u3067\u306f\u3001\u6a19\u6e96\u7684\u306a\u671d\u98df\u306b\u30d4\u30fc\u30ca\u30c3\u30c4\uff0842.5 g\uff09\u307e\u305f\u306f\u30d4\u30fc\u30ca\u30c3\u30c4\u30d0\u30bf\u30fc\uff0842.5 g\uff09\u3092\u6442\u53d6\u3059\u308b\u3068\u3001\u98df\u5f8c\u30a4\u30f3\u30b9\u30ea\u30f3\u8840\u4e2d\u6fc3\u5ea6\u304c\u4e0a\u6607\u3057\u3001\u6a19\u6e96\u7684\u306a\u663c\u98df\u5f8c\u306e\u98df\u6b32\u304c\u6e1b\u308a\u307e\u3057\u305f\u3002\u3055\u3089\u306b\u3001\u30d4\u30fc\u30ca\u30c3\u30c4\u30d0\u30bf\u30fc\u306f\u3001\u6a19\u6e96\u7684\u306a\u663c\u98df\u5f8c\u306e\u98df\u5f8cPYY\u8840\u4e2d\u6fc3\u5ea6\u3092\u6709\u610f\u306b\u4e0a\u6607\u3055\u305b\u3001\u98df\u5f8c\u8840\u7cd6\u6fc3\u5ea6\u3092\u4f4e\u4e0b\u3055\u305b\u307e\u3057\u305f\u3002GLP-1\u3068PYY\u306f\u5c0f\u8178\u306b\u3042\u308bL\u7d30\u80de\u304b\u3089\u5171\u5206\u6ccc\u3055\u308c\u308b\u3053\u3068\u304b\u3089 \u3001\u30d4\u30fc\u30ca\u30c3\u30c4\u30d0\u30bf\u30fc\u304c\u98df\u5f8c\u306eGLP-1\u5206\u6ccc\u3082\u4fc3\u9032\u3059\u308b\u53ef\u80fd\u6027\u306f\u5341\u5206\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u30e1\u30bf\u30dc\u30ea\u30c3\u30af\u30b7\u30f3\u30c9\u30ed\u30fc\u30e0\u306e\u6210\u4eba\u306b\u70ad\u6c34\u5316\u7269\u3092\u542b\u3080\u98df\u4e8b\u306b\u30d4\u30b9\u30bf\u30c1\u30aa85.0g\u3092\u52a0\u3048\u305f\u3068\u3053\u308d\u3001GLP-1\u3068\u30b0\u30eb\u30b3\u30fc\u30b9\u30a4\u30f3\u30b9\u30ea\u30f3\u523a\u6fc0\u30da\u30d7\u30c1\u30c9\u306e\u8840\u4e2d\u6fc3\u5ea6\u304c\u4e0a\u6607\u3057\u305f\u3053\u3068\u3092\u767a\u898b\u3057\u307e\u3057\u305f\uff08\uff11\uff12\uff09\u3002<\/p>\n<p>\u00a0<\/p>\n<ul>\n<li>GLP-1\u3092\u5897\u3084\u3059\u98df\u3079\u65b9<\/li>\n<\/ul>\n<p>\u30002022\u5e74\u306b\u30a4\u30f3\u30c9\u30cd\u30b7\u30a2\u306e\u30b8\u30e3\u30ab\u30eb\u30bf\u3067\u5b9f\u65bd\u3055\u308c\u305f\u7814\u7a76\u306b\u3088\u308b\u3068\u3001\u70ad\u6c34\u5316\u7269\u3092\u98df\u3079\u308b\u524d\u306b\u91ce\u83dc\u3092\u98df\u3079\u308b\u3068\u3001\u70ad\u6c34\u5316\u7269\u306e\u5f8c\u306b\u91ce\u83dc\u3092\u6442\u53d6\u3057\u305f\u4eba\u306b\u6bd4\u3079\u3066\u3001\u7279\u306b\u98df\u5f8c60\u5206\u30672\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u306e\u8840\u7cd6\u5024\u3068GLP-1\u30ec\u30d9\u30eb\u306b\u6709\u610f\u306a\u5f71\u97ff\u304c\u51fa\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002<\/p>\n<p>\u3000\u7814\u7a76\u8005\u3089\u306f\u3001\u70ad\u6c34\u5316\u7269\u306e\u524d\u306b\u91ce\u83dc\u3092\u98df\u3079\u308b\u3053\u3068\u306f\u3001\u8840\u7ba1\u5408\u4f75\u75c7\u3092\u9632\u3050\u6709\u671b\u3067\u30b7\u30f3\u30d7\u30eb\u306a\u7cd6\u5c3f\u75c5\u98df\u3067\u3042\u308b\u3068\u7d50\u8ad6\u4ed8\u3051\u307e\u3057\u305f\uff08\uff11\uff13\uff09\u3002<\/p>\n<p>\u3000\u4ee5\u4e0a\u304c\u6700\u8fd1\u306e\u77e5\u898b\u3067\u3059\u3002\u767a\u9175\u6027\u98df\u7269\u7e4a\u7dad\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u3068\u8cea\u306e\u3044\u3044\u8102\u8cea\u3092\u542b\u3080\u98df\u54c1\u3092\u6bce\u65e5\u306e\u98df\u751f\u6d3b\u306b\u53d6\u308a\u5165\u308c\u3066\u4e0b\u3055\u3044\u3002\u307e\u305fGLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3092\u4f7f\u7528\u3057\u3066\u3044\u308c\u3070\u3001\u4f55\u3092\u98df\u3079\u3066\u3082\u8a00\u3044\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\u3092\u4f7f\u7528\u3057\u306a\u304c\u3089\u6804\u990a\u4fa1\u306e\u9ad8\u3044\u98df\u4e8b\u3092\u6442\u308b\u3053\u3068\u306f\u3001\u3053\u308c\u3089\u306e\u85ac\u306e\u52b9\u679c\u3092\u6700\u5927\u9650\u306b\u5f15\u304d\u51fa\u3059\u305f\u3081\u306b\u4e0d\u53ef\u6b20\u3067\u3059\u3002\u4e0a\u8ff0\u306e\u3088\u3046\u306a\u98df\u54c1\u3092\u7a4d\u6975\u7684\u306b\u53d6\u308a\u5165\u308c\u3066\u304f\u3060\u3055\u3044\u306d\u3002<\/p>\n<p>\u00a0<\/p>\n<p>\uff08\uff11\uff09<a href=\"https:\/\/journals.physiology.org\/doi\/full\/10.1152\/physrev.00034.2006\">https:\/\/journals.physiology.org\/doi\/full\/10.1152\/physrev.00034.2006<\/a><\/p>\n<p>\uff08\uff12\uff09<a href=\"https:\/\/www.drugsincontext.com\/a-clinical-review-of-glp-1-receptor-agonists-efficacy-and-safety-in-diabetes-and-beyond\/\">https:\/\/www.drugsincontext.com\/a-clinical-review-of-glp-1-receptor-agonists-efficacy-and-safety-in-diabetes-and-beyond\/<\/a><\/p>\n<p>\uff08\uff13\uff09<a href=\"https:\/\/www.npr.org\/sections\/health-shots\/2023\/10\/30\/1208883691\/diet-ozempic-wegovy-weight-loss-fiber-glp-1-diabetes-barley\">https:\/\/www.npr.org\/sections\/health-shots\/2023\/10\/30\/1208883691\/diet-ozempic-wegovy-weight-loss-fiber-glp-1-diabetes-barley<\/a><\/p>\n<p>\uff08\uff14\uff09<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24024772\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/24024772\/<\/a><\/p>\n<p>\uff08\uff15\uff09<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26273900\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/26273900\/<\/a><\/p>\n<p>\uff08\uff16\uff09<a href=\"https:\/\/mana.md\/do-you-need-fermentable-fiber-in-your-diet\/\">https:\/\/mana.md\/do-you-need-fermentable-fiber-in-your-diet\/<\/a><\/p>\n<p>\uff08\uff17\uff09<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23466396\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/23466396\/<\/a><\/p>\n<p>\uff08\uff18\uff09<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/12600850\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/12600850\/<\/a><\/p>\n<p>\uff08\uff19\uff09<a href=\"https:\/\/www.health.harvard.edu\/nutrition\/high-protein-foods-the-best-protein-sources-to-include-in-a-healthy-diet\">https:\/\/www.health.harvard.edu\/nutrition\/high-protein-foods-the-best-protein-sources-to-include-in-a-healthy-diet<\/a><\/p>\n<p>\uff08\uff11\uff10\uff09<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8235588\/\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8235588\/<\/a><\/p>\n<p>\uff08\uff11\uff11\uff09<a href=\"https:\/\/nutritionandmetabolism.biomedcentral.com\/articles\/10.1186\/s12986-016-0153-3\">https:\/\/nutritionandmetabolism.biomedcentral.com\/articles\/10.1186\/s12986-016-0153-3<\/a><\/p>\n<p>\uff08\uff11\uff12\uff09<a href=\"https:\/\/nutritionandmetabolism.biomedcentral.com\/articles\/10.1186\/s12986-016-0153-3\">https:\/\/nutritionandmetabolism.biomedcentral.com\/articles\/10.1186\/s12986-016-0153-3<\/a><\/p>\n<p>\uff08\uff11\uff13\uff09<a href=\"https:\/\/nutritionandmetabolism.biomedcentral.com\/articles\/10.1186\/s12986-016-0153-3\">https:\/\/nutritionandmetabolism.biomedcentral.com\/articles\/10.1186\/s12986-016-0153-3<\/a><\/p>\n<p>\uff08\u3053\u306e\u8a18\u4e8b\u306f\u3001MRIC by\u3000\u533b\u7642\u30ac\u30d0\u30ca\u30f3\u30b9\u5b66\u4f1a\u3000<a href=\"http:\/\/medg.jp\/mt\/?p=12668\">Vol.24193 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